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Endocannabinoid System and CBD: What is the Relation Between Them



CBD and Endocannabinoid System

In 1990 while researching THC’s possible effects on our body, scientists discovered the complex Endocannabinoid system. Although discovered as early as 3 decades ago, researchers have seen quite a lot of promise exploring the cannabinoid receptors’ depths. They have discovered that ECS affects sleep, mood, memory, appetite, and fertility. If you want to know how you can benefit by applying holistic medication (i.e., CBD), we have a thorough introduction.

If you want to know the endocannabinoid system definition and its working, then go through the article. Besides, you will also learn the importance of ECS for proper body functioning. This article also includes how CBD has a direct relation with ECS.

Overview of the Endocannabinoid System

All in all, the endocannabinoid system directly controls the homeostasis in the body. Due to this, your body maintains the internal environment. Hence, you can easily fight diseases and bodily ailments. Contrarily, faulty homeostasis leads to the onset of several mental and physical ailments.

The endocannabinoid system works on the molecular level. With that said, you get to balance and regulate different bodily functions properly. For example, cognition, cell communication, immunity levels, appetite, etc. Notably, these functions are quintessential for the proper functioning of the body.

In brief, the endocannabinoid system is an endogenous lipid-based neurotransmitter. These retrograde neurotransmitters bind with cannabinoid receptors. Furthermore, the cannabinoid system stops the onset of disease and increases immunity. Anandamide, as well as 2-AG, are two main neurotransmitters of Endocannabinoids.

How Does The Endocannabinoid System Work?

To begin with, ECS, enzymes, and receptors are the main component of ECS. If you want to know the ECS working in detail, then read below.

Endocannabinoid Receptors

Your body has thousands of receptors that offer a sense of touch, smell, pain, etc. Moreover, receptors need to get attached to Endocannabinoids. Thus, receptors get to respond to the ECS at the time of need. To date, scientists have discovered two types of ECS receptors viz. CB1 and CB2.

Most importantly, CB1 receptors are found inside the Central Nervous System. On the other hand, CB2 receptors are located in the peripheral nervous system. Meanwhile, CB2 receptors play a crucial role in maintaining the body’s immunity.

The prime components of the endocannabinoid system directly influence the CB1 and CB2 receptors. For example, Anandamide neurotransmitters influence the CB1 receptor. Besides, the AG-2 neurotransmitter has a direct influence over CB2 receptors. Recently, scientists have also discovered 8 more receptors. These receptors offer genuine aid in regulating CNS, gastric system, immunity, pain, etc.


After the ECS play their role, several enzymes break them down. Hence, your body attains perfect balance. With that said, AEA is broken down by Amide hydrolase. Likewise, AG-2 is broken down by monoacylglycerol acid lipase.

Homeostasis: The Role of the Endocannabinoid System 

First things first, the endocannabinoid system directly regulates several bodily processes, such as muscle formation, mood, nerve function, bone growth, etc. In general, your body attains internal equilibrium by Homeostasis. Notably, homeostasis balances any external injury, inflammation, or allergic reaction. ECS plays a vital role in helping the body to function normally. Consequently, you become more attentive and productive.

Irrespective of the external environment, the ECS balances the internal environment of the body. For instance, you start to sweat during summers. Thus, the body’s internal temperature gets regulated. Likewise, your stomach starts to growl when you feel hungry. Last but not least, homeostasis takes place with the help of CB1 and CB2 receptors.

What Is The Relation Between The Endocannabinoid System and CBD?

Most of the first-timers want to know what CBD is. In short, CBD or Cannabidiol obtain from Cannabis species viz. Hemp and Marijuana. CBD is one of the most important Cannabinoids of Cannabis species. Unlike Marijuana, Hemp plants have low THC concentration. To be specific, the concentration is lower than 0.3%. As a result, you do not have to deal with any psychoactive effects. In addition to this, you can even pass the drug test without any hassle. For this reason, most of the CBD products are made from Hemp species.

Endocannabinoid System

Types of CBD Extracts 

  • Full-spectrum 

Notably, full-spectrum Hemp extract contains 0.3% THC, CBG, CBD, CBN, flavonoids, and terpenes. Thus, you will get genuine holistic medication with an entourage effect.

  • Broad-Spectrum 

Broad-spectrum also contains additional terpenes, flavonoids, and antioxidants but has no THC. In effect of this, you do not have to worry about any drug tests.

  • Pure-Isolate 

You can use pure-isolate CBD to get genuine relief from medical conditions. As the name suggests, these products only contain high-grade CBD.

Types of Cannabidiol Products Used for The Endocannabinoid System

  • Edibles

In comparison to oils and salves, CBD Gummies are easy to administer and are thoroughly consistent. Moreover, you can even buy them in several delicious flavors.

  • Pills and capsules

Like edibles, capsules and pills are easy to administer. CBD capsules come in a wide range of concentrations. Thus, you can buy them as per the tolerance level or need.

  • Oils

Primarily, you can use CBD oil via different means. For example, you can use oils sublingually, through the vaping pens, or via. Massage. Moreover, you can also consume oils through the Pechoti method. The Pechoti method is great for first-timers as CBD doesn’t get synthesized in the body. That said, it is hard to administer the daily dosage.

  • Shatter

If you are dealing with inflammation or muscle pain, then buy the best quality CBD Shatter. Meanwhile, shatters are the best products for first-timers. This is so because they do not have THC, flavonoids, or terpenes.

  • Cream

As compared to oils, CBD cream has a water-base. Hence your skin will absorb it quickly. Besides, Cannabidiol creams also contain coolants. In the effect of this, you will get a soothing after effect. In comparison to pills and capsules, Cannabidiol cream offers quick, localized relief.

CBD and Endocannabinoid System

In short, the endocannabinoid system and CBD have a similar influence on the body’s receptors. With that said, CBD contains phytocannabinoids that mimic the Endocannabinoid system. Therefore, your body gets the upper hand in maintaining perfect homeostasis. As a result, your body gets healed naturally. You can consume Cannabidiol in several forms, aiding the endocannabinoid system to work properly. Last but not least, CBD products do not have any severe side effects.

  • Things you need to keep into consideration

Before buying CBD for the proper functioning of the endocannabinoid system, make sure that it is authentic. This is so because some websites sell spurious products. Consequently, you have to deal with health issues. Few other factors you need to take into consideration are mentioned below.

  • Third-party certificates

Likewise, it would help if you looked for third-party certification. Therefore, you can see the concentration of pH, THC, heavy metals, etc.

  • Buy from a legit source.

If possible, then buy products from the manufacturer’s site. Manufacturer’s web portals offer a genuine product. Additionally, you will get free shipping as well as additional discounts. In addition to this, you can also go through genuine customer reviews.

  • Look for the extraction source.

As mentioned above, Marijuana plants have a high THC concentration, higher than 30%. Therefore, you have to suffer from heavy psychoactive effects. Moreover, THC also metabolizes in the body. Thereby CBD will show in the drug test.

  • Buy indigenous products

Always buy Cannabidiol products that are manufactured in the U.S. Now you do not have to worry about any adulteration or heavy metals.

How Useful is The Endocannabinoid System for CBD Consumers?

For starters, you won’t get any genuine benefit of CBD without the endocannabinoid system. As mentioned above, Endocannabinoid influence the CB1 and CB2 receptors to maintain the process of homeostasis. Moreover, ECS has direct control over the nervous, muscular, renal, and digestive systems. Likewise, the endocannabinoid system also controls the reproductive and cardiovascular system. Thus, it can be inferred that Endocannabinoids play a vital role in the body.

Final Thought

In brief, the endocannabinoid system is the foundation of the human body. This is so because it helps to maintain proper homeostasis. As a result, your appetite, mood, muscle, and bone growth is regulated. Notably, the ECS works by controlling CB1 as well as CB2 receptors. CB1 receptors are located in the Central Nervous System. On the other hand, CB2 receptors control bodily immunity.

The ECS, as well as CBD, has a great interrelationship. With that said, CBD contains phytocannabinoids that mimic the ECS. In effect of this, you can easily maintain homeostasis. You can buy three types of CBD extracts viz. full, broad-spectrum, and pure-isolate.

Before making a purchase, see to it that non-GMO hemp plants are used for the extraction process. Hemp plants have low THC concentration. Thereby, you do not have to worry about addiction or drug tests. Finally, Endocannabinoids hold great influence for CBD consumers. This is so because ECS controls every vital function of the human body.

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