The vaccine of coronavirus treatment has been given as rollout begins across the UK/US. With the first dose of Pfizer Covid 19 vaccines were administered. There are so many questions abound about safety. Pfizer and BioNTech have developed this medicine treat Covid 19. About 4 million people have received the vaccine, but there are so many facts and information that you need one must know about it.
What is in Pfizer Covid 19 vaccine?
Pfizer covid 19 vaccines train the immune system to fight against the coronavirus. It is an RNA vaccine that uses tiny molecules used by living cells to make gene sequence in DNA. However, the vaccine’s exact ingredients have not been made public, but the vaccine may contain aluminum to make it even more effective.
How Do Pfizer Covid 19 vaccines Work?
As per the evidence and clinical trials, the Pfizer covid 19 vaccines was 95% effective at preventing laboratory-confirmed Covid-19 illness. It is a new type of jab known as RNA vaccine.
It uses a small fragment of the virus’s genetic code. This vaccine starts making a part of the virus inside the body. The immune system recognizes the outside element and starts to attack. Then the genetic material in a tiny protective bubble of fat gets into the cells. To get effective results vaccine is given in two doses three weeks apart.
How Was the Vaccine Developed?
BioNTech, a Germany-based company, has designed an mRNA vaccine after the genetic sequence of the SARS-Cov-2 virus became public. BioTech partnered with Pfizer in march, early clinical trials two leading mRNA neutralizing the antibody response that was better than recovering from natural coronavirus infection without serious side-effect.
Based on the trial, the results company has decided to move forward with the combined phase ⅔ random trials on 30 microgram doses.
This ⅔ phase started in the US, enrolling around 44000 people from Brazil, Germany, Turkey, South Africa. The enrollment increases 30,000 in September, including people infected with HIV, hepatitis C, hepatitis B, and teens as young as 16.
How Safe and Effective is the Vaccine?
In the trials, there are no such reported safety concerns. However, anyone having the vaccine must be prepared for some unpleasant experiences such as redness and swelling at the injection site, fatigue, headache, fever, etc.
As per the FDA advisory committee report, such reactions are more common and severe in younger people. Severe adverse effect disabling effect or life-threatening events occurred in less than 1% of participants. The FDA has also considered a few instances that include a shoulder injury swelling in the lymph nodes following vaccination.
A limited number of allergic reactions have also been reported, including anaphylaxis in the US, the UK since Pfizer and BioNTech treatment is administered. Anaphylaxis refers to life-threatening reactions that occur within seconds or minutes of its exposer. CDC recommends consulting with a physician if ever had severe allergic reactions.
To find out the ingredients causing the unpleasant reactions, NIH has started conducting a study in which people with severe allergic reactions under medical supervision.
The vaccine is needed to be kept in the cold. In fact, extreme cold is necessary to keep the RNA molecules from degrading. This requirement of cold chain poses one of the major hurdles in distributing the vaccine. Many potential vaccination sites cannot provide the ultracold freezer and have no source of dry ice.
However, Pfizer has tried to deal with the challenge by creating special thermal shippers; it maintains the ultracold temperature for up to 10 days.
Who Can Safely Get the Pfizer/BioNTech Covid-19 Vaccine
Pfizer is working tirelessly to develop a vaccine that could help all, including infants from diseases. As per the Pfizer company, the vaccine is recommended for people minimum of 16 years and older. In addition to this, the company has started studying its use for adolescents 12-15 years old. Let us know if you are indifferent health conditions, is the coronavirus vaccine is safe for everybody?
Pfizer and BioNTech trying to make a medicine to protect new bord children from various diseases. But there is not much data available to determine the risk involved in it. For this reason, pregnant women are not included in the trials for this coronavirus treatment. CDC assessment should be offered a chance to get the vaccine, but it has not yet been tested on the public.
Well, the Pfizer biotech vaccine safety for lactating people has not been studied yet. There is insufficient data on which could decide whether they should be vaccinated or not.
However, the RNA vaccine is not thought to be harmful to a breastfeeding infant, for this CBD indicates that if lactating people are in a priority group can be vaccinated if they want.
People With Allergies
According to a report in Britain, developed anaphylaxis after being immunized with Pfizer and BioNTech vaccine. According to the guidelines posted on their website into three categories, proceed with caution, proceed with vaccination, and don’t vaccinate.
For example, people with allergies to food, insects, animals, and other common allergies can be vaccinated. Similarly, people with allergies to oral drugs can take the vaccine as per the guidelines. In addition to this, non-serious allergic reaction to injections, but the people with anaphylaxis are not apart from this. The people having a family history of anaphylaxis but not experienced themselves also.
On the other hand, the people having severe allergic reactions to this vaccine in its first dose should not deliver the next dose. For detailed information, the FDA has released a document including the major ingredients.
Children and teens younger than 16
As per the guidelines and Pfizer vaccine news, it is authorized for 16 years old or above. Also, the company is continuously studying its use for 12 to 15 years aged teens. But for now, it is not authorized for people aged less than 16 years.
People with HIV
Pfizer company has done some volunteer HIV-positive clinical trials with stable infection ⅔ phase, but there are not enough data to analyze the population.
But according to the CDC, people with HIV can be vaccinated, but with proper efficacy, safety but in immune-compromised people is still unclear.
People on Immunosuppressant Therapy
People who are under immunosuppressant therapy and have taken drugs to suppress their immune system, for example – organ recipients, can be vaccinated only if they don’t have any other condition, for that vaccination is not allowed.
Who Will Get Pfizer Covid 19 vaccines First?
The people vaccinated first will be over -80 workers in NHS staff, care homes, and vaccinators. The care home residents will be next on the list after clarifying how small batches of the vaccine can be transported. There are nine priority groups out of the people aged between 50-54 at the bottom of the current list. Finally, in the second phase, the vaccine will be delivered to the other groups in the population.
Initially, the vaccine will be delivered to care homes and GPs, and go-to vaccination centers.
Could Pfizer Covid 19 vaccines Have Long-Term Side Effects?
Honestly, no medicine is 100% safe- even the medicine we take without thinking- paracetamol, for instance, poses health risks. However, the data of 43500 trials report has not discovered any safety concerns. But there are some mild side effects, such as headaches, muscle aches, swelling and pain in the injection site, etc.
The world has seen extraordinary conditions in the last year due to this pandemic. But it is great news that the coronavirus vaccine is possible. After the trial of dozens of vaccines, these vaccines have been considered to show better results.
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